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Classification

Box 1 describes the classification proposed by Thomas (14) and modified by us (15-17). It is important to note that different forms of DN often coexist in the same patient (e.g. distal polyneuropathy and carpal tunnel syndrome)

Figure A.  

 

Table A. Classification of diabetic neuropathies.

Rapidly reversible

  1. Hyperglycemic neuropathy

Generalized symmetric polyneuropathy

  1. Acute sensory neuropathy

  2. Chronic sensorimotor neuropathy or distal symmetric polyneuropathy (DPN)

    1. Small-fiber neuropathy

    2. Large-fiber neuropathy

  3. Autonomic neuropathy

Focal and multifocal neuropathies

  1. Focal-limb neuropathy

  2. Cranial neuropathy

  3. Proximal-motor neuropathy (amyotrophy)

  4. Truncal radiculoneuropathy

  5. Coexisting chronic inflammatory demyelinating neuropathy (CIDP)