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	NORMAL GLUCOSE HOMEOSTASIS
	GLUCOSE HOMEOSTASIS IN TYPE 2 DIABETES MELLLITUS
	Insulin Secretion in Type 2 Diabetes Mellitus
	Insulin Resistance and Type 2 Diabetes Mellitus
	SITE OF INSULIN RESISTANCE
	Hepatic Glucose Production
	Peripheral (Muscle) Glucose Uptake
	Splanchnic (Hepatic) Glucose Uptake
	Summary: Whole Body Glucose Utilization
	Glucose Disposal During OGTT
	Summary of Insulin Resistance
	DYNAMIC INTERACTION BETWEEN INSULIN SENSITIVITY AND INSULIN SECRETION IN TYPE 2 DIABETES
	ROLE OF THE ADIPOCYTE IN THE PATHOGENESIS OF TYPE 2 DIABETES MELLITUS: THE HARMONIOUS QUARTET
	FFA and Muscle Glucose Metabolism
	Randle Cycle Revisited: Biochemical/ Molecular Basis of FFA-Induced Insulin Resistance
	FFA and Blood Flow
	FFA and Hepatic Glucose Metabolics
	Summary: FFA and the Pathogenesis of Obesity and Type 2 Diabetes Mellitus
	CELLULAR MECHANISMS OF INSULIN RESISTANCE
	Insulin Receptor/Insulin Receptor Tyrosine Kinase
	Insulin Receptor Signal Transduction
	Insulin Signal Transduction Defects in Type 2 Diabetes
	Glucose Transport
	Glucose Phosphorylation
	Glycogen Synthesis
	Glycolysis/Glucose Oxidation